June 2024. Volume 20. Number 2

Pregnant woman vaccine against group B streptococcus produces protective immunity at birth

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Madhi SA, Anderson AS, Absalon J, Radley D, Simon R, Jongihlati B, et al. Potential for Maternally Administered Vaccine for Infant Group B Streptococcus. N Engl J Med. 2023;389:215-27.

Reviewers: Albi Rodríguez MS1, Cuestas Montañés EJ2.
1Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: María Salomé Albi Rodríguez. Email: msalbir@gmail.com
Reception date: 01/04/2024
Acceptance date: 15/04/2024
Publication date: 24/04/2024

Abstract

Authors´ conclusions: maternal Group B Streptococcus (GBS) vaccine elicited anti-capsular polysaccharide antibodies against group B streptococcus in pregnant women that were transferred to infants, at levels associated with a reduced risk of invasive group B streptococcal disease.

Reviewers´ commentary: hexavalent vaccine against invasive disease due to group B streptococcus in pregnant women seems safe, although studies are needed to establish the optimal composition and doses, and its effectiveness in the newborn.

How to cite this article

Albi Rodríguez MS, Cuestas Montañés E. Vacunar a la gestante frente a estreptococo del grupo B produce inmunidad protectora al nacimiento. Evid Pediatr. 2024;20:18.

AVC | Critically appraised articles

Madhi SA, Anderson AS, Absalon J, Radley D, Simon R, Jongihlati B, et al. Potential for Maternally Administered Vaccine for Infant Group B Streptococcus. N Engl J Med. 2023;389:215-27.

Reviewers: Albi Rodríguez MS1, Cuestas Montañés EJ2.
1Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: María Salomé Albi Rodríguez. Email: msalbir@gmail.com
Reception date: 01/04/2024
Acceptance date: 15/04/2024
Publication date: 24/04/2024

How to cite this article

Albi Rodríguez MS, Cuestas Montañés E. Vacunar a la gestante frente a estreptococo del grupo B produce inmunidad protectora al nacimiento. Evid Pediatr. 2024;20:18.

24/04/2024

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