December 2023. Volume 19. Number 4

Crystalloid balanced solutions: an option in severe dehydration due to acute diarrhea

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Florez ID, Sierra J, Pérez-Gaxiola G. Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children. Cochrane Database Syst Rev. 2023;5(5):CD013640.

Reviewers: Pérez-Moneo Agapito B1, Cuestas Montañés EJ2.
1Servicio de Pediatría. Hospital Universitario Infanta Leonor. Universidad Complutense de Madrid. Madrid. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 20/11/2023
Acceptance date: 05/12/2023
Publication date: 13/12/2023

Abstract

Authors´ conclusions: the evidence is very uncertain about the effect of balanced solutions on mortality during hospitalization in severely dehydrated children. However, they likely result in a slight reduction of the time in the hospital compared to 0.9% saline. Also, balanced solutions likely reduce the risk of hypokalemia after intravenous correction. Furthermore, the evidence suggests that balanced solutions compared to 0.9% saline probably produce no changes in the need for additional intravenous fluids or in other biochemical measures such as sodium, chloride, potassium, and creatinine levels. Last, there may be no difference in the incidence of hyponatremia.

Reviewers´ commentary: the use of balanced solutions compared to 0.9% saline solution seems to slightly reduce the time in the hospital, as well as achieve higher pH and bicarbonate levels, without showing differences in terms of mortality or the appearance of renal failure in severe dehydration due to acute diarrhea. In our setting, balance solutions are available, so their use should be assessed; in low-income countries, their availability should be taken into account when recommending them.

How to cite this article

Pérez-Moneo Agapito B, Cuestas Montañés E. Soluciones cristaloides balanceadas: una opción en deshidratación grave por diarrea aguda. Evid Pediatr. 2023;19:47.

AVC | Critically appraised articles

Florez ID, Sierra J, Pérez-Gaxiola G. Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children. Cochrane Database Syst Rev. 2023;5(5):CD013640.

Reviewers: Pérez-Moneo Agapito B1, Cuestas Montañés EJ2.
1Servicio de Pediatría. Hospital Universitario Infanta Leonor. Universidad Complutense de Madrid. Madrid. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 20/11/2023
Acceptance date: 05/12/2023
Publication date: 13/12/2023

How to cite this article

Pérez-Moneo Agapito B, Cuestas Montañés E. Soluciones cristaloides balanceadas: una opción en deshidratación grave por diarrea aguda. Evid Pediatr. 2023;19:47.


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Sierra JM. Líquidos balanceados en la rehidratación del niño deshidratado grave por diarrea. Evid Pediatr. 2023;19:37.
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